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Humane endpoints: Animals were euthanized if tumor volume exceeded 2000 mm³, if tumors reached 10% of body weight, if body weight loss exceeded 20–25%, or if signs of cachexia or severe distress were observed

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2 5 These are properties one can reasonably argue should help a follicle, but they were mostly characterized in skin models, wound models, and gene-expression assays, not in controlled hair-growth experiments on human scalps