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Inter-nanocarrier and nanocarrier-to-cell transfer assays demonstrate the risk of an immediate unloading of dye from labeled lipid nanocapsules

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Activation of the UPR generally serves as a readout for ER stress, but it is not clear what diminished UPR signaling implies in terms of actual accumulation of unfolded proteins, particularly because some stressors, such as palmitate loading, activate the UPR apparently independent of the protein folding process (Volmer et al., 2013)