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A careful skeptic would say: the in-clinic procedure has solid evidence, the at-home extension is biologically plausible and consistent with the procedure, but the dataset is younger than the recommendation implies

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Why the Percentages Are Not Directly Comparable The short answer: 20.1% over 48 weeks and 11.8% over 68 weeks are not measuring the same thing, and anyone presenting eloralintide as "roughly twice as effective" is comparing across trials that were never designed to be compared