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Frontiers | Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms

Several preclinical studies have shown that Quer in the myocardium can enhance the GSH antioxidant system by regulating multiple upstream molecular targets, such as peroxisome proliferator-activated receptor-gamma (PPAR-γ), phosphatidylinositide 3-kinase (PI3K)/serine/threonine kinase (AKT), and Nrf2 [120, 123, 124]

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Circulating levels of IGF-1 directly regulate bone growth and density [PMID: 12235108] Laboratory literature summary: Circulating levels of IGF-1 directly regulate bone growth and density