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Whether rescuing GABA-related gene defects through genetic methods can improve behavior is worthy of further exploration (102, 109)

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4.1.3 BRWD3 BRWD3 (Bromodomain and WD Repeat Domain Containing 3), also known as ramshackle, acts as a substrate receptor for the Cul4-RING E3 ubiquitin ligase complexes and mediates light-induced degradation of cry (Ozturk et al., 2013)