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Furthermore, while mitochondrial 1C was recently found to be a key source of B cell lymphoma glycine (Ducker et al., 2017), high 1C flux can generate potentially toxic levels of intracellular glycine, which necessitates disposal through the glycine cleavage system (GCS) or via efflux systems

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Within 12 weeks of treatment, the drugs completely restored the mice's hair, and the hair remained for several months after stopping the treatment

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