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Using the ~15.7% figure derived earlier, and remembering that the parenteral nutrition reference range for adults is 0.3–0.5 mg (300–500 µg) of copper per day: [10] The widely repeated community figure of 1.7 mg/day delivers, by this estimate, roughly 267 µg of copper directly into tissue — the same order of magnitude as what a clinical team would deliver intravenously over a full day to a patient receiving all their nutrition parenterally, and which they would reduce, with monitoring of serum concentrations , in the presence of cholestasis because of accumulation risk