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In the altered scenario of cholestasis, the retention of more hydrophobic bile salts, such as the glyco- and tauro-conjugates of deoxycholate, plays a major part in the onset of liver injury, causing hepatotoxicity due to mitochondrial dysfunction and production of ROS, with consequent oxidative damage [181,182]

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BPC-157, administered within one minute of alcohol exposure, reversed brain swelling, protected liver tissue at the microscopic level, and counteracted vascular congestion across all organs examined