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Additionally, the amygdalae harvested from MTLE patients demonstrated neuronal death and gliosis ( Neurotrophic Factors Evidently, alterations in expression of neurotrophic factors, such as BDNF and GDNF, have been observed in epilepsy and neuropsychiatric disorders, and aberrant expression of these factors may be amenable to stem cell therapy

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Despite more than one hundred preclinical publications, there are no completed Phase III human trials for BPC-157 in any indication, and none specifically for low back pain or sciatica